Entries Tagged 'Erectile dysfunction treatment' ↓

NEW YORK (Reuters Health) - Laboratory studies conducted at Queen's University Belfast, UK suggest that taking the erectile dysfunction drug Viagra may adversely affect sperm function and possibly male fertility.

Recreational users of Viagra need to be informed of the drug's potentially harmful effects on sperm function, the investigators say.

In their experiments, Dr. David R. J. Glenn and colleagues observed that exposure of cultured sperm to Viagra, compared to no exposure, led to a "sustained enhancement of motility," both in numbers of progressively motile sperm and their velocity.

However, exposure to Viagra — at concentrations equivalent to the average maximum total blood concentration present 30 minutes after a single oral dose of 100 milligrams — also caused a premature "acrosome reaction." Acrosomes are structures that cover the head of the sperm and contain a variety of enzymes that help the sperm penetrate the outer membrane of the egg.

That Viagra may induce early activation of the acrosome reaction has "important clinical implications because sperm that acrosome-react before contact with the oocyte are incapable of fertilization," the researchers note in the journal Fertility and Sterility.

"Given that the majority of sperm acrosome react on exposure to (Viagra), the drug may cause significant impairment to their fertilizing potential," they write.

This is a concern, Glenn and colleagues say, given that Viagra and other like-drugs are widely available on the Internet and are increasingly being used "recreationally" by young healthy men of reproductive age as sexual enhancers — not just by older men who have erectile dysfunction.

SOURCE: Fertility and Sterility, May 2007. Continue reading →

Pelvic floor exercises have long been recommended for women - now researchers say they could help men too.

The exercises were found to help men with erectile dysfunction as much as taking in Viagra.

The researchers say the findings mean men have an alternative to drug therapy.

For around 50 years, women have been advised to perform pelvic floor exercises to strengthen their muscles for childbirth.

The pelvic floor is a "hammock" of muscles which support the bowel and bladder.

Pelvic floor, or Kegel, exercises involve clenching the muscles you would use to prevent yourself urinating.

This latest research indicates it is also important for men to maintain the muscle tone and function of their pelvic floor muscles with the exercises.

Home exercises

The team from the University of the West of England in Bristol studied 55 men with an average age of 59 who had experienced erectile dysfunction for at least six months.

The men, all patients at the Somerset Nuffield Hospital, Taunton, Somerset, were given five weekly sessions of pelvic floor exercises and assessed at three and six months, and asked to practise the exercises daily at home.

It was found 40% of the men regained normal erectile function - some of who had severe erectile dysfunction, and another 35% showed some improvement.

Two thirds of the men had said they also had problems with urination. These improved significantly after they began the exercises.

Dr Grace Dorey, a specialist continence physiotherapist who carried out the research, told BBC News Online: "The exercises were found to be equally as effective as taking Viagra.

"Pelvic floor exercises improve function in a physical way, in a more natural way.

"Men should be doing preventative exercise. It really is use it or lose it."

She said men should be exercising their pelvic floor exercises from puberty onwards.

Strength

A spokesperson for the Impotence Association said: "The value and effectiveness of pelvic floor exercises should not be underestimated when considering the management of sexual problems such as impotence and premature ejaculation.

"The exercises are thought to strengthen the muscles that surround the penis and improve the blood supply in the pelvis, which is an important factor in relation to erectile dysfunction."

The Impotence Association helpline number is 0208 767 7791.

Originaly from Source

WASHINGTON (AFP) - Injections of botulinum toxin A, or Botox, into the prostate gland eased the symptoms of enlarged prostate in men for up to a year, according to the results of a small study published Wednesday.

Researchers at the Chang Gung University Medical College, Taiwan, and the University of Pittsburgh School of Medicine, Pennsylvania, based their study on 37 men with benign prostatic hyperplasia (BHP), or enlarged prostate.

All patients received a single injection of Botox into their prostate, the researchers said in their paper published in a summary ahead of this week's American Urological Association's annual conference, in Annaheim, California. Continue reading →

Retired New Jersey firefighter is reporting decreased insulin doses and lower blood glucose levels within one month after his adult stem cell treatment for diabetes (type 2), diabetes induced erectile dysfunction and peripheral artery disease in Cologne, Germany.

Cologne, Germany (PRWEB) June 19, 2007 — Retired Fire Captain, Calvin Miller of Union City, New Jersey is reporting decreased insulin doses and lower blood glucose levels within one month after his adult stem cell treatment for diabetes (type 2) , diabetes induced erectile dysfunction and peripheral artery disease in Cologne, Germany.

Mr. Miller was recently treated at the XCell-Center using adult stem cells derived from a small amount of his own bone marrow. The stem cells were introduced directly into his pancreas using a minimally invasive catheter procedure via the right femoral artery. To battle the common diabetes complications of peripheral artery disease and erectile dysfunction, stem cells were also introduced into his thighs and calves, and into the arteries that supply the penis, respectively.

"Before scuba diving this past Sunday morning, I injected only 32% of my normal insulin dose. During the day, I ate normally - for a diabetic - without injecting any more insulin. That evening, I measured my blood sugar and I was astounded that it was only 126. A month ago, even with my full insulin doses, I never had readings below 170," said Miller.

These are the third, fourth and fifth diseases in two years for which Mr. Miller has chosen to undergo stem cell therapy. After being treated with stem cells for coronary artery disease in January 2005, he was featured in BusinessWeek Magazine (June 2005) . In September 2005, he was treated for ischemic cardiomyopathy using minimally invasive surgery.

"Actually, what really got my attention this past weekend was that I also felt a regeneration of heart function…and that was after a 3 km swim," Miller added with a grin.

About the XCell-Center
The XCell-Center is the first privately-owned center in Europe to specialize in regenerative medicine using autologous adult stem cell therapy. Newly completed in 2006, the XCell-Center features the latest medical equipment and technology. The XCell-Center is a fully licensed clinic with German specialized physicians working in accordance with German law and European guidelines. It is located on the second floor wing of the Eduardus Hospital in Cologne, Germany.

The XCell-Center currently treats Diabetes and its complications (Erectile Dysfunction and Peripheral Artery Disease), Stroke, Spinal Cord Injuries, Ischemic Heart Disease and degenerative diseases such as Multiple Sclerosis, Parkinson's and Alzheimer's.

Before the end of this year, the XCell-Center will publish clinical data coming from their SCIDEM I and II trials. In these trials, diabetes (type I and II) patients will be treated with their own stem cells and compared with a control group receiving traditional therapy. The findings will be presented at different international scientific meetings. Later this year, another clinical trial for stroke patients will commence.

For more information on Stem Cell Therapy:
XCell-Center Website: http://www.xcell-center.com

Stem Cell Therapy for Diabetes Blog: http://www.stem-cell-diabetes.blogspot.com

XCell-Center GmbH
at the Institute for Regenerative Medicine
Custodisstrasse 3-17
Cologne, Germany 50679

E-Mail: info @ xcell-center.de

Phone: 1-866-680-8202 (USA Toll-Free) or (+49) 0221-802-5095 (Germany)

Fax: 1-713-583-9322 (USA) or (+49) 0221-2921-2550 (Germany)

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XCell-Center GmbH
Ruud de Jong
+49 0221-802-5095
E-mail Information
Trackback URL: http://prweb.com/pingpr.php/SGFsZi1UaGlyLUNvdXAtQ291cC1UaGlyLVplcm8= Continue reading →

SUNDAY, June 3 (HealthDay News) — Gene therapy using nerve growth factors reversed erectile dysfunction in rats within four weeks, say University of Pittsburgh School of Medicine researchers.

Erectile dysfunction (ED) affects between 15 million and 30 million men in the United States. Many men suffer nerve damage-related ED after surgery for prostate cancer.

The Pittsburgh team found that the genes for the "glial cell line derived neurotrophic factor" (GDNF) and the GDNF family ligand, called neurturin, were both effective in treating erectile dysfunction in the rats. The genes were placed in a genetically engineered herpes simplex virus, which was then injected into the rats' damaged cavernous nerve. Continue reading →

WASHINGTON (Reuters) - The male impotence drug Viagra may be useful for treating jet lag as well, according to Argentine researchers who gave it to hamsters made to feel like rodent globe-trotters.

The researchers manipulated the schedule of turning lights on and off to induce jet lag in the laboratory animals, they reported on Monday in the Proceedings of the National Academy of Sciences

National Academy of Sciences.

Adult male hamsters given Viagra, also called sildenafil, recovered from jet lag up to 50 percent faster than hamsters that were not given it, the researchers said.

The scientists stopped giving the hamsters the highest dose they had been using in the experiment due to a certain side effect.

"However, we used the intermediate dose for the rest of the experiments because at that dose animals did not manifest the effects of sildenafil-induced penile erections," they wrote.

Flying across multiple time zones can confuse one's sleep-wake cycle, resulting in the condition called jet lag, marked by insomnia, sleepiness and difficulty concentrating.

Researchers Patricia Agostino, Santiago Plano and Diego Golombek of the Universidad Nacional de Quilmes in Buenos Aires gave doses of Viagra to the hamsters at night, then switched on bright lights six hours early to simulate eastbound flight.

They judged how well the hamsters adjusted to the changes by observing when they began running on exercise wheels.

The drug helped the rodents cope with jet lag only when given before the equivalent of an eastbound flight, not the reverse when they delayed turning on lights to simulate westbound travel, the study found.

The researchers said the findings suggested that Viagra could be useful to help people cope with jet lag or shift work. They said the dose needed for such uses could be lower than the one used for treatment of erectile dysfunction.

Viagra interferes with an enzyme that lowers levels of a naturally occurring compound that plays a role in the regulation of the circadian cycle, the body's internal clock, the researchers said.

Viagra is marketed by Pfizer, the world's largest drug maker. The U.S. Food and Drug Administration

Food and Drug Administration approved it to treat erectile dysfunction in 1998. Continue reading →

BioLife Remedies, Inc. is pleased to announce that DIA-X™ is now available for retail and wholesale at www.blfrproducts.com. DIA-X™ is an herbal product developed by the company for men with Erectile Dysfunction from Diabetes.

Vancouver, B.C. and Guangzhou, China (PRWEB) May 29, 2007 — BioLife Remedies, Inc. announces the opening of sales of Dia-X(former name Di-Agra) for the remedy of Erectile Dysfunction for Diabetics.

BioLife Remedies, Inc. (PINKSHEETS: BLRS) is pleased to announce that DIA-X™ is now available for retail and wholesale at www.blfrproducts.com. DIA-X™ is an herbal product developed by the company for men with Erectile Dysfunction from Diabetes.

The President and CEO of the Company, Jack Guo commented, "DIA-X™ is developed for diabetic male with E.D., and the product was derived from a century-old TCM herbal formula used traditionally for men with Diabetes Mellitus who have problems in their sexual activity. Our researchers did extensive studies and tests on the formula and identified the herbs that are effective in getting and keeping an erection for sexual activity while helping people to control blood glucose level."

Mr. Jack Guo also commented, "If the diabetic men have developed symptoms of Erectile Dysfunction, it seems that other symptoms of complication may also be presented, such as frequent urination, so we suggest customers to taking Dia-X and Zutrol together for more effective recovery of health." For more information of the products, please visit www.blfrproducts.com.

About BioLife Remedies, Inc
Biolife Remedies, Inc. combines Traditional Chinese Medicine and Western academic research and development practices with the newest scientific technology to produce effective medical and health-care products to combat serious diseases. The BioLife Group has developed 108 master medical formulas to treat various diseases including diabetes, prostateria, osteoporosis, cerebrovascular disease, cardiac vascular disease, hypertension, menopausal syndrome, and sexual disorders in men and women. For further information about BioLife Remedies Inc. please refer to its Web site at http://www.blfrproducts.com

Contact:
BioLife Remedies,Inc
Jack Guo
http://www.blfrproducts.com
Tel: 604-630-8881
Fax: 604-630-8877

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BioLife Remedies,Inc.
Jack Guo
1-604-338-1989
E-mail Information
Trackback URL: http://prweb.com/pingpr.php/Q291cC1TdW1tLVBpZ2ctU2luZy1UaGlyLVplcm8= Continue reading →

SUNDAY, June 3 (HealthDay News) — Gene therapy using nerve growth factors reversed erectile dysfunction in rats within four weeks, say University of Pittsburgh School of Medicine researchers.

Erectile dysfunction (ED) affects between 15 million and 30 million men in the United States. Many men suffer nerve damage-related ED after surgery for prostate cancer.

The Pittsburgh team found that the genes for the "glial cell line derived neurotrophic factor" (GDNF) and the GDNF family ligand, called neurturin, were both effective in treating erectile dysfunction in the rats. The genes were placed in a genetically engineered herpes simplex virus, which was then injected into the rats' damaged cavernous nerve. Continue reading →